My 428 had twin stainless 2.5's with Hooker headers and twin straight through Magnaflow mufflers and X-pipe. It was loud and very raspy/crisp. But I didn't notice any drone.
I had a twin in/out 2.5 inch Magnaflow straight through muffler on my 302W AU and also on my 351W F150 both with no resonators or cross pipe and they too had a nice note with no drone. Neither were loud though.
My 390 F100 has a pissy 2 inch, I think, true twin system with twin Flowmaster 40's. Has slight rumble but the motor is stock. It has no drone and is not loud. It needs to be change to give it more character. You hear it coming down the road and people turn their heads but it's not showing its true colours....yet
I guess my point is, I wouldn't bother with resonators unless you get it all together and the neighbours or wife complains.